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According to a new study, lower doses of approved immunotherapy for malignant melanoma can give better results against tumors, while reducing side effects. This is reported by researchers at Karolinska Institutet in the Journal of the National Cancer Institute.
Insect pupae hiss like snakes for defense. A Kobe University team now reveals the mechanisms, opening the door to further studies involving predator reactions to defensive sounds.
Patients undergoing treatment for lymphoma often experience adverse side effects that can be so severe that they stop or slow treatment. But a new study shows that a virtual program focusing on diet and exercise is a feasible strategy for minimizing the side effects of cancer therapies and increasing treatment retention.
The U.S. stillbirth rate dropped slightly last year, offering some hope after several years of uncertainty, according to new data from the U.S. Centers for Disease Control and Prevention (CDC).
Disaster-hit Sri Lanka has unveiled a major compensation package to rebuild homes damaged by a deadly cyclone, even as the island prepared on Saturday for further landslides and flooding.
The humble pocket calculator may not be able to keep up with the mathematical capabilities of new technology, but it will never hallucinate.
The Nordic countries are no strangers to the long, dark winter.
An international collaboration led by Cornell researchers used a combination of psilocybin and the rabies virus to map how—and where—the psychedelic compound rewires the connections in the brain.
Interactions among viruses can help them succeed inside their hosts or impart vulnerabilities that make them easier to treat. Scientists are learning the ways viruses mingle inside the cells they infect, as well as the consequences of their socializing.
Worcester Polytechnic Institute (WPI) researchers have created a new carbon-negative building material that could transform sustainable construction. The breakthrough, published in the high-impact journal Matter, details the development of enzymatic structural material (ESM), a strong, durable, and recyclable construction material produced through a low-energy, bioinspired process.
Treatment with an immune and cancer cell-targeting antibody therapy eradicates residual traces of the blood cell cancer multiple myeloma, according to interim results from a clinical trial conducted by researchers at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine. The findings will be presented Dec. 6, 2025, at the American Society of Hematology (ASH) annual meeting in Orlando.
A new targeted alpha therapy is showing promise for patients whose thyroid cancer no longer responds to radioactive iodine, the standard beta-emitting treatment. In a first-in-human study, investigators found that a single dose of the alpha-emitting radionuclide 211At (astatine) was both well-tolerated and effective, achieving disease control without molecularly targeted drugs. The findings were published in the December issue of The Journal of Nuclear Medicine.
Make way for digital health. Smart watches and health apps aren't just for fitness enthusiasts and people with access to advanced care—the World Health Organization (WHO) is looking to these and other digital tech devices to enhance health and wellness across the globe.
New research from Johns Hopkins Medicine adds to existing evidence that smoking fewer cigarettes does not eliminate cardiovascular disease risk, and quitting entirely is the most effective strategy for improving health.
How much the planet warms with each ton of carbon dioxide remains one of the most important questions in climate science, but there is uncertainty in predicting it. This uncertainty hinders governments, businesses and communities from setting clear emission-reduction targets and preparing for the impacts of climate change.
A new study by Phoenix's Barrow Neurological Institute and the University of Calgary has found which injectable treatments showed the most benefit for migraine patients and should be routinely offered by Emergency Departments (ED) when feasible. The findings from the study will update the guidelines for the American Headache Society.
Cancer isn't just about broken genes—it's about broken architecture. Imagine a city where roads suddenly vanish, cutting off neighborhoods from essential services. That's what happens inside cells when the 3D structure of DNA collapses.
Weight loss drugs aren't just for people anymore; They may soon be available for your furry friend.
This week, JPL scientists reported that glaciers speed up and slow down at predictable intervals. CERN's ATLAS experiment detected evidence for the decay of a Higgs boson into a muon-antimuon pair. And researchers discovered that exercise slows tumor growth by shifting glucose uptake to muscles.
Goldenberries taste like a cross between pineapple and mango, pack the nutritional punch of a superfood, and are increasingly popular in U.S. grocery stores. But the plants that produce these bright yellow-orange fruits grow wild and unruly—reaching heights that make large-scale farming impractical.
What can mapped drainage systems on Mars teach scientists about the red planet's watery past? This is what a recent study published in the Proceedings of the National Academy of Sciences hopes to address as a team of scientists from the University of Texas at Austin (UT Austin) conducted a first-time mapping study involving Martian river basins. This study has the potential to not only gain insight into ancient Mars and how much water existed there long ago, but also develop new methods for mapping ancient river basins on Mars and potentially other worlds.
For years, the search for a stem cell donor has felt like a quest for a rare key—one that fits a lock with eight intricate tumblers, each representing a genetic marker. For many patients with blood cancers, especially those from diverse backgrounds, the right key simply didn't exist. The door to a cure remained closed.
In a recent study, researcher Dr. Hui Zhou and his colleagues conducted a genetic analysis of the genomes of individuals associated with the ancient Hanging Coffin tradition in Southeast and Southern Asia. In addition, they sequenced the genomes of modern-day Bo people to determine their genetic relationship to the ancient Hanging Coffin practitioners.
Patients who underwent hematopoietic cell transplantation for sickle cell disease saw high rates of survival without disease symptoms and low rates of severe side effects or complications years after their procedure, according to a study presented at the 67th ASH Annual Meeting and Exposition held 6–9 December, in Orlando, Florida.
A study assessing the real-world commercial roll-out of gene therapies for sickle cell disease and beta thalassemia offers lessons learned to inform best practices as manufacturers and medical centers prepare to meet growing demand for gene therapies in the coming years. The study was presented at the 67th ASH Annual Meeting and Exposition held 6–9 December, in Orlando, Florida.
Preliminary results from two trials of the gene therapy exagamglogene autotemcel (exa-cel) suggest the therapy offers an effective cure for beta-thalassemia and sickle cell disease in children younger than 12. Researchers say the therapy's potential to offer a cure at an early age—before organ damage accumulates—could make exa-cel even more beneficial in children than adults.
Taking the sickle cell drug hydroxyurea during or shortly before pregnancy does not appear to cause specific issues in newborns, according to the first prospective study of pregnancies involving hydroxyurea exposure. The study was presented at the 67th ASH Annual Meeting and Exposition held 6–9 December, in Orlando, Florida.
Wear and tear, injury, certain medical conditions, and age can take a toll on shoulder function. Oftentimes, surgery can be avoided, with many people responding well to nonoperative treatments, such as physical therapy or injections, to decrease their pain and improve the use of their shoulder. Sometimes, surgery to repair the torn tendons may be necessary.
A new study from UNC-Chapel Hill researchers shows that advanced artificial intelligence tools, specifically large language models (LLMs), can accurately determine the locations where plant specimens were originally collected, a process known as georeferencing.
When a natural disaster strikes, time is of the essence if people are trapped under rubble. Conventional search-and-rescue methods use radar-based detection or employ acoustics that rely on sounds made by victims.
In the canopies of a South American rainforest, a tiny soldier termite has stunned a team of international scientists with its whale-like features.
Billions of alkaline-loving microbes could offer a new way to protect nuclear waste buried deep underground. This approach overcomes the limitations of current cement barriers, which can crack or break down over time.
Syntax Bio, a synthetic biology company programming the next generation of cell therapies, has published new research in Science Advances detailing the company's CRISPR-based Cellgorithm technology, which lays the groundwork for programmable control of gene activity in human stem cells and offers an alternative to the slow, variable manual processes researchers use today.
Modern neural networks, with billions of parameters, are so overparameterized that they can "overfit" even random, structureless data. Yet when trained on datasets with structure, they learn the underlying features.
A new study provides a crucial roadmap for Japan to address an escalating ecological challenge while advancing food sustainability: overcoming the psychological barriers to game meat consumption.
Astronomers have captured images of two stellar explosions—known as novae—within days of their eruption and in unprecedented detail. The breakthrough provides direct evidence that these explosions are more complex than previously thought, with multiple outflows of material and, in some cases, dramatic delays in the ejection process.
A new article published in Nature Communications offers insight into how government planners can better account for the many uncertainties that accompany the transition from fossil-fuel power systems to renewable or decarbonized systems. The paper, titled "Identifying key uncertainties in energy transitions with a Puerto Rico case study," is the work of a team from the University of Virginia including first author Kamiar Khayambashi, a Ph.D. student in the School of Engineering and Applied Science.
Iron-on patches can repair clothing or add personal flair to backpacks and hats. And now they could power wearable tech, too. Researchers reporting in ACS Applied Materials & Interfaces have combined liquid metal and a heat-activated adhesive to create an electrically conductive patch that bonds to fabric when heated with a hot iron. In demonstrations, circuits ironed onto a square of fabric lit up LEDs and attached an iron-on microphone to a button-up shirt.
The rise of artificial intelligence, cloud platforms, and data processing is driving a steady increase in global data center electricity consumption. While running computer servers accounts for the largest share of data center energy use, cooling systems come in second—but a new study by researchers at the National Laboratory of the Rockies (NLR), formerly known as NREL, offers a potential solution to reduce peak energy consumption.
As power demand surges in the AI era, the protonic ceramic electrochemical cell (PCEC), which can simultaneously produce electricity and hydrogen, is gaining attention as a next-generation energy technology. However, this cell has faced the technical limitation of requiring an ultra-high production temperature of 1,500°C.
Researchers at UC Santa Barbara have invented a display technology for on-screen graphics that are both visible and haptic, meaning that they can be felt via touch.
Wastewater from washing machines is considered a major source of microplastics—tiny plastic particles that are suspected of harming human and animal health. Researchers at the University of Bonn have now developed a filter to curb this problem. Their invention was inspired by the gill arch system in fish.
To increase driving range, electric vehicle (EV) batteries rely on high-nickel cathodes. However, this high nickel content has a critical drawback: battery performance degrades rapidly during charging and discharging. The primary cause has now been identified as internal structural distortion, which generates "oxygen holes" that shorten the battery's lifespan—similar to how a warped pillar can crack a building's walls.
Meta announced Friday it will integrate content from major news organizations into its artificial intelligence assistant to provide Facebook, Instagram and WhatsApp users with real-time information.
A research team at the Korea Institute of Materials Science (KIMS) has developed a high-performance heat-dissipating composite material that achieves both eco-friendliness and low-cost processing.
Vanderbilt researchers have developed a lightweight wearable device that shifts body armor weight off the shoulders and back of soldiers, helping reduce pain and injury risk.
Adopting digital twin technology to manage the power consumption of idle devices could save organizations thousands of pounds a year and help reduce their carbon footprint, new research suggests.
What does the space shuttle have in common with the original iPhone? According to Francisco Polidoro Jr., professor of management of Texas McCombs, they're both breakthrough inventions that integrate webs of interdependent features.
ChatGPT maker OpenAI and an Australian data center operator have agreed to develop a multibillion-dollar AI center in Sydney.
Future events such as the weather or satellite trajectories are computed in tiny time steps, so the computation must be both efficient and as accurate as possible at each step lest errors pile up. A Kobe University team has introduced a new method that uses deep learning for creating tailored, accurate simulations that respect physical laws, while also being more computationally efficient.
A new report from the University of Liverpool and the United Nations Migration Agency–International Organization for Migration (IOM) demonstrates how harnessing digital data collected from mobile phone applications and social media platforms can transform the way humanitarian agencies track and respond to population displacement during crises.
The world is loud. A walk down the street bombards one's ears with the sound of engines revving, car horns blaring, and the steady beeps of pedestrian crossings. While smartphone alerts to excessive sound and public awareness of noise exposure grows, few tools help people take protective action.
Researchers at the University of Maryland, Baltimore County (UMBC) have extracted the building blocks of precise hand gestures used in the classical Indian dance form Bharatanatyam—and found a richer "alphabet" of movement compared to natural grasps. The work could improve how we teach hand movements to robots and offer humans better tools for physical therapy.
The next era of power system operations is taking shape through digitalization, artificial intelligence, and intelligent automation. To help utilities and navigate this change, Fraunhofer FIT and Accenture have published a white paper titled "Transformation Journey Towards Software-Defined Power System Operations."
Technology, no matter how advanced, always comes with a shelf life. Mechanical equipment used in clean-energy systems is no different. But as global efforts toward carbon neutrality accelerate, assessing the durability of infrastructure such as wind turbines, solar power plants, and nuclear facilities has become increasingly important.
Railway infrastructure could be made safer and more reliable using AI, artificial intelligence, according to research published in the International Journal of Information and Communication Technology. The research outlines a new automated, real-time fault detection system based on deep learning that can identify problems with track, bridges, tunnels, and signaling equipment. The work could address long-standing challenges in maintaining complex transportation networks.