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A new clinical study published in the International Journal of Gynecological Cancer reports encouraging results for women facing platinum-resistant ovarian cancer (PROC). Researchers evaluated a novel DNA-based therapy, Elenagen, administered in combination with the standard chemotherapy gemcitabine in women with PROC and elevated CA-125.

Just outside Salt Lake City sits an old, two-story, brick hotel. It's been given new life as a homeless shelter for seniors. The Medically Vulnerable People shelter—or MVP shelter, as it's known—is for people 62 and older or for younger adults with chronic health issues.

Happiness and well-being depend on how much volition, choice and control people feel they have over their life—their sense of autonomy. Researchers have acknowledged this connection, but there's been disagreement about whether it's universal or simply a reflection of the situation in wealthier, more individualistic countries. Understanding this nuance would help policymakers focus efforts to boost well-being where they matter most.

Scientists at The Lundquist Institute for Biomedical Innovation have identified a previously unknown molecular safeguard that protects the heart during pregnancy, shedding new light on the causes of peripartum cardiomyopathy (PPCM), a rare and life-threatening form of pregnancy-related heart failure.

Changes in genes have been linked to the development of different diseases for a while. However, it's not exactly clear what the mechanisms, or the causes behind those specific genetic changes, are. Recent studies using fission yeast, which can act as an ideal model for human cells, have highlighted one possible mechanism linked to disease onset.

Heat-resilient biofertilizers could help crops cope with rising temperatures but engineering them has been slow and uncertain. A new study at the National Institutes for Quantum Science and Technology (QST) shows that pairing experimental evolution with controlled gamma-ray mutagenesis can accelerate the path to heat-tolerant nitrogen-fixing bacteria, shortening development timelines and opening practical routes to more reliable, climate-ready microbial products for agriculture, food processing, pharmaceuticals, and biofuel production.

People experiencing delusions during an episode of psychosis may be "living out" a deeply held emotion, according to new research that provides a "radically different perspective" on one of the most puzzling elements of psychosis.

Most COVID-19 vaccine hesitancy is rooted in concerns that can be addressed and effectively reduced over time, according to a new study following more than 1.1 million people in England between January 2021 and March 2022 during the COVID-19 pandemic, published in The Lancet.

Today, trans people face politicization of their lives and vilification from politicians, media and parts of broader society.

Elyse Stevens had a reputation for taking on complex medical cases. People who'd been battling addiction for decades. Chronic pain patients on high doses of opioids. Sex workers and people living on the street.

Clinicians seem to generally use intraocular pressure (IOP) as a continuous risk factor in their treatment patterns in patients with glaucoma, according to a study published online Jan. 8 in JAMA Ophthalmology.

Select gut bacteria protect mice against post-influenza virus secondary bacterial pneumonia, according to a study published by researchers in the Institute for Biomedical Sciences at Georgia State University.

A recent publication in Nature Medicine describes a novel immunotherapy targeting pancreatic cancer that has shown promising results in a first in-human phase 1/2 trial.

Scientists at Pacific Northwest Research Institute (PNRI) have overturned a long-held belief in genetics: that inheriting two harmful variants of the same gene always worsens disease. Instead, the team found that in many cases, two harmful variants can actually restore normal protein function.

A new long-term prediction tool estimates the risk of dying from prostate cancer, offering a more accurate way to interpret prostate-specific antigen (PSA) test results compared to existing models. The tool, tested on over 200,000 men, outperformed current methods and could help doctors tailor screening and treatment decisions based on individual risk and life expectancy.

As the climate changes, scientists are concerned about how well plants and animals will adapt to rapid warming. A new University of Vermont study has explored the early embryonic life stage of a globally common fruit fly, Drosophila melanogaster, looking at how the eggs responded to temperature variability at the genomic level.

Mitochondrial dysfunction is associated with various chronic diseases and cancers, including neurodegenerative diseases and metabolic syndrome. Gently extracting a single mitochondrion from within a living cell—without causing damage and without the guidance of fluorescent makers—has long been a challenge akin to threading a needle in a storm for scientists.

Beyond smart watches and rings, artificial intelligence is being used to make self-testing for major diseases more readily available—from headsets that detect early signs of Alzheimer's to an iris-scanning app that helps spot cancer.

Whether they are laundry detergents, mascara, or Christmas chocolate, many everyday products contain fatty acids from palm oil or coconut oil. However, the extraction of these raw materials is associated with massive environmental issues: Rainforests are cleared, habitats for endangered species are destroyed, and traditional farmers lose their livelihoods.

Cereals have natural resistance to pathogenic fungi, but powdery mildew, for example, can overcome this resistance. A team at the University of Zurich has now discovered a new mechanism that enables powdery mildew to outsmart the immune system of wheat. This opens the door to targeted development of resistant varieties with a reduced risk of resistance breakthrough.

A research team at the University of Würzburg has, for the first time, uncovered how E. coli bacteria sneak into the prostate. The study opens the door to potential new treatments for bacterial prostatitis.

X-ray tomography is a powerful tool that enables scientists and engineers to peer inside of objects in 3D, including computer chips and advanced battery materials, without performing anything invasive. It's the same basic method behind medical CT scans.

A new study demonstrates the effectiveness of a widely-used eye injection to manage the previously untreatable rare condition, hypotony, in a project by clinical researchers at UCL and Moorfields Eye Hospital.

A whole-genome sequencing approach shows early promise over current commercial methods for identifying more patients likely to benefit from PARP inhibitor cancer treatments, according to a study led by Weill Cornell Medicine and NewYork-Presbyterian investigators. The findings suggest further development of this approach is merited.

Researchers at VIB and KU Leuven have identified a molecular process that allows motor neurons to maintain protein production, a process that fails in amyotrophic lateral sclerosis (ALS). The study, published in Nature Neuroscience, reveals an early weakness in neurodegeneration and highlights a potential target for future therapies.

McGill engineering researchers have introduced an open-source model that makes it easier for experts and non-experts alike to evaluate greenhouse gas emissions from U.S. natural gas supply chains and yields more accurate results.

By fine-tuning the surroundings of single cobalt atoms, researchers reveal how tiny design changes can steer oxygen reactions toward cleaner and more efficient hydrogen peroxide production.

We know the genes, but not their functions—to resolve this long-standing bottleneck in microbial research, a joint research team has proposed a cutting-edge research strategy that leverages artificial intelligence (AI) to drastically accelerate the discovery of microbial gene functions.

Newly published interdisciplinary research led by the University of Tennessee, Knoxville, and University of Maryland shows that viral infection of blue-green algae in the ocean stimulates productivity in the ecosystem and contributes to a rich band of oxygen in the water.

For patients with human epidermal growth factor receptor 2-positive (HER2-positive) metastatic or locally advanced unresected gastroesophageal adenocarcinoma (mGEA), zanidatamab and chemotherapy, with or without tislelizumab, may prolong survival compared with trastuzumab + chemotherapy, according to a study presented at the American Society of Clinical Oncology annual Gastrointestinal Cancers Symposium, held from Jan. 8 to 10 in San Francisco.

Azelaic acid is a renewable monomer used in the production of lubricants, polymers, and skincare. While conventionally produced via the energy-intensive ozonolysis of oleic acid, recent advances enable its production from high-oleic vegetable oil via the two-step oxidative cleavage (TSOC) process, improving process safety.

An international team of researchers has uncovered hidden clues about life in the hills of ancient southwest Samos, Greece.

The blood-brain and blood-retinal barriers are protective systems that prevent harmful substances from entering the brain and eyes. These barriers are created by cells that are joined tightly together by proteins. Dysfunctional barriers can cause a range of diseases, including stroke, brain tumors and blinding eye diseases such as diabetic retinopathy.

Structural health monitoring (SHM) and condition monitoring are crucial processes that ensure reliability and safety of engineering systems in a variety of fields, including aerospace, civil engineering, and industry. These systems are often assessed using vibration-based methods, where damage is detected by analyzing changes in a structure's vibration characteristics.

For decades, researchers have focused on the problem of overgrazing, in which expanding herds of cattle and other livestock degrade grasslands, steppes and desert plains. But a new global study reveals that in large regions of the world, livestock numbers are substantially declining, not growing—a process the authors call destocking.

This new NASA Hubble Space Telescope image captures a jet of gas from a forming star shooting across the dark expanse. The bright pink and green patches running diagonally through the image are HH 80/81, a pair of Herbig-Haro (HH) objects previously observed by Hubble in 1995. The patch to the upper left is part of HH 81, and the bottom streak is part of HH 80.

A collaboration between Stuart Parkin's group at the Max Planck Institute of Microstructure Physics in Halle (Saale) and Claudia Felser's group at the Max Planck Institute for Chemical Physics of Solids in Dresden has realized a fundamentally new way to control quantum particles in solids. Writing in Nature, the researchers report the experimental demonstration of a chiral fermionic valve—a device that spatially separates quantum particles of opposite chirality using quantum geometry alone, without magnetic fields or magnetic materials.

A notification popped up on my LinkedIn the other day: Africans were doing a traditional celebratory dance at the Africa Stablecoin summit in Johannesburg.

Researchers have developed a new algorithmic model that can improve predictions of cooling demand for greener buildings. This kind of control will be a key factor in energy efficiency, allowing interior climate control systems to optimize cooling periods and so reduce energy demands.

Initially, the residents of a five-story New York City apartment building feared the conversion from their oil-based heating system to electric heat pumps would mean less warmth in the winter.

Organic light-emitting diodes (OLEDs) are widely used in smartphones and TVs thanks to their excellent color reproduction and thin, flexible planar structure. However, internal light loss has limited further improvements in brightness. KAIST researchers have now developed a technology that more than doubles OLED light-emission efficiency while maintaining the flat structure that is a key advantage of OLED displays.

Researchers at Los Alamos National Laboratory have, for the first time, used a breakthrough technique with a goal of better identifying the origin of nuclear materials—a tool that could someday help efforts to prevent the spread of nuclear material around the globe.

No ice is colder and harder than speedskating ice. The precision it takes has meant that Olympic speedskaters have never competed for gold on a temporary indoor rink—until the 2026 Milan Cortina Winter Games.

Pendants and brooches packed with artificial intelligence abounded at the Consumer Electronics Show, using cameras and microphones to watch and listen through the day like a vigilant personal assistant.

Toy makers at the Consumer Electronics Show were adamant about being careful to ensure that their fun creations infused with generative artificial intelligence don't turn naughty.

Google said Sunday that it is expanding the shopping features in its AI chatbot by teaming up with Walmart, Shopify, Wayfair and other big retailers to turn the Gemini app into a virtual merchant as well as an assistant.

In recent years, electronics engineers have been trying to identify semiconducting materials that could substitute for silicon and enable the further advancement of electronic devices. Two-dimensional (2D) semiconductors, such as molybdenum disulfide (MoS₂), have proved to be among the most promising solutions, as their thinness and resistance to short-channel effects could yield highly performing and smaller electronics.

Researchers at the Department of Energy's Oak Ridge National Laboratory have developed an innovative energy storage system design that introduces a safer, more efficient method for electrical charge transfer.

Every year, companies lose revenue when goods are copied or illegally resold. Now, a new digital and legally binding fingerprint developed at the University of Copenhagen makes products impossible to counterfeit. Royal Copenhagen is among the first brands in the world to use the solution.