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A new preclinical study from researchers at The University of Texas MD Anderson Cancer Center, published in Nature Communications, identifies a powerful strategy to overcome drug resistance in breast cancer by simultaneously targeting two key cell-cycle regulators, CDK2 and CDK4/6.

A new comprehensive review from researchers at the Icahn School of Medicine at Mount Sinai details how decades of cancer vaccine research are converging into a new era of more precise, personalized, and effective immunotherapies, particularly when combined with other cancer treatments. The work examines the evolution of therapeutic cancer vaccines, with a special focus on neoantigen-based vaccines—highly personalized vaccines designed using genetic mutations unique to a patient's tumor.

Organic matter carried in rivers to the Russian part of the Arctic Ocean may be creating more clouds and keeping the region cooler, a new study has found.

Researchers from several European institutions, led by scientists from the University of Barcelona and the University of Alcalá, have demonstrated that the hunter-gatherers who inhabited the interior of the Iberian Peninsula during the Last Glacial Maximum (between approximately 26,000 and 19,000 years ago) were part of large-scale social networks capable of connecting vast territories in western Europe.

Researchers have reported new experimental results addressing the origin of rare proton-rich isotopes heavier than iron, called p-nuclei. Led by Artemis Tsantiri, then-graduate student at the Facility for Rare Isotope Beams (FRIB) and current postdoctoral fellow at the University of Regina in Canada, the study presents the first rare isotope beam measurement of proton capture on arsenic-73 to produce selenium-74, providing new constraints on how the lightest p-nucleus is formed and destroyed in the cosmos.

Researchers from Leiden University Medical Center (LUMC) and the Leiden-based biotech company Ncardia have joined forces to develop a new platform that enables the automated production of 3D cardiac microtissues. This platform will allow large numbers of drugs to be tested quickly.

Many people with different mental health problems can be absent from work for a long time. But new results give hope that more people can recover and return to work sooner. A new treatment method that involves metacognitive therapy and job focus can save society three times as much as it costs by getting people with mental health problems back to work sooner.

In experiments with mice, Johns Hopkins Medicine scientists report new evidence that precursors of myelin-producing cells—one of the few brain cell types that continue to be produced in the adult brain—undergo differentiation widely and at a constant pace, rather than "as needed" in response to injury or advancing age.

Space debris—the thousands of pieces of human-made objects abandoned in Earth's orbit—pose a risk to humans when they fall to the ground. To locate possible crash sites, a Johns Hopkins University scientist has helped to devise a way to track falling debris using existing networks of earthquake-detecting seismometers.

Generative AI is reshaping software development—and fast. A new study published in Science shows that AI-assisted coding is spreading rapidly, though unevenly: in the U.S., the share of new code relying on AI rose from 5% in 2022 to 29% in early 2025, compared with just 12% in China. AI usage is highest among less experienced programmers, but productivity gains go to seasoned developers.

Researchers at the University of Basel and the Laboratoire Kastler Brossel have demonstrated how quantum mechanical entanglement can be used to measure several physical parameters simultaneously with greater precision.

Elon Musk sees his humanoid robots hitting the market next year, one of several "optimistic" forecasts by the US tech mogul at his first-ever Davos appearance on Thursday.

Tweaking a pattern of wound healing established millions of years ago may enable scar-free injury repair after surgery or trauma, Stanford Medicine researchers have found. If results from their study, which was conducted in mice, translate to humans, it may be possible to avoid or even treat the formation of scars anywhere on or within the body.

By resurrecting a 3.2-billion-year-old enzyme and studying it inside living microbes, researchers at the University of Wisconsin–Madison have created a new way to improve our understanding of the origins of life on Earth and possibly recognize signs of life elsewhere.

Scientists at the Icahn School of Medicine at Mount Sinai have developed an experimental immunotherapy that takes an unconventional approach to metastatic cancer: instead of going after cancer cells directly, it targets the cells that protect them.

The second annual report from the National Cancer Database (NCDB) of the American College of Surgeons (ACS) documents a substantial rise in medication treatments, such as chemotherapy, immunotherapy, and hormone therapy, used before surgery to treat many cancers, often allowing less invasive surgery and helping clinicians assess how a patient's cancer responds to medication to guide the most effective treatment options.

Researchers from Helmholtz Munich and the Technical University of Munich (TUM) have developed "fast-RSOM," a new imaging technology that can capture detailed images of the smallest blood vessels directly through the skin—without the need for invasive procedures. By revealing early signs of cardiovascular risk, this technology could help doctors intervene sooner, guide personalized therapies, and improve long-term heart health.

Why do some tumors spread while others remain localized? The mechanisms governing the metastatic potential of tumor cells remain largely unknown—yet understanding this is crucial for optimizing patient care.

People have long said that "bread is life." Now, researchers at Tufts University are using the bubbling mixtures of flour and water known as sourdough starters to explore what shapes life at the microscopic level. Their findings, published in Ecology, demonstrate a simple way to predict how microbial species will live together, providing insights that could inform baking, food safety, and human health.

The diversity of water strider species apparently developed as early as the Cretaceous period, much earlier than previously thought. SNSB researchers have succeeded in clarifying the phylogenetic history of this insect family, with molecular analyses providing comprehensive insights into their relationships and evolution. Their study has now been published in the journal Systematic Entomology.

Monash University and Indian Institute of Technology Bombay researchers have developed a solar-powered desalination prototype that can produce safe drinking water continuously, overcoming a major technical barrier that has limited many existing systems.

Our planet is unique for its ability to sustain abundant life. From studies of the rock record, scientists believe life had already emerged on Earth at least 3.5 billion years ago and probably much earlier.

Scientists have discovered over 6,000 planets that orbit stars other than our sun, known as exoplanets. More than half of these planets were discovered thanks to data from NASA's retired Kepler mission and NASA's current TESS (Transiting Exoplanet Survey Satellite) mission. However, the enormous treasure trove of data from these missions still contains many yet-to-be-discovered planets. All of the data from both missions is publicly available in NASA archives, and many teams around the world have used that data to find new planets using a number of techniques.

The Dark Energy Survey Collaboration collected information on hundreds of millions of galaxies across the universe using the U.S. Department of Energy-fabricated Dark Energy Camera, mounted on the U.S. National Science Foundation Víctor M. Blanco 4-meter Telescope at CTIO, a program of NSF NOIRLab. Their completed analysis combines all six years of data for the first time and yields constraints on the universe's expansion history that are twice as tight as past analyses.

What if traffic could compute? This may sound strange, but researchers at Tohoku University's WPI-AIMR have unveiled a bold new idea: using road traffic itself as a computer.

A new study published in Otolaryngology–Head and Neck Surgery reveals that glucagon-like peptide-1 receptor agonists (GLP-1RAs)—a class of medications primarily used for weight loss and diabetes management—may significantly improve post-surgical outcomes for patients with chronic rhinosinusitis with nasal polyps (CRSwNP) and obesity.

UBC Okanagan researchers have advanced their work on developing a noninvasive, accessible way to reduce uncontrolled hand tremors. In their newly published study, the team has demonstrated how a new wearable device may reduce involuntary hand tremors linked with neurological conditions such as Parkinson's disease.

Beneath Antarctica's Ross Ice Shelf lies one of the least measured oceans on Earth—a vast, dark cavity roughly twice the volume of the North Sea.

Piezofluorochromism, the phenomenon of materials reversibly changing their fluorescent color when pressure is applied, is used to create the pressure sensors used in automotive and medical industries. By monitoring color changes, researchers can visually recognize phenomena, such as chemical changes, that actually take place. However, as devices get increasingly complicated, there is an increasing demand for ways to produce more sensitive sensors.

Physicists from University of Jyväskylä and Aalto University (Finland) have experimentally realized a two-dimensional topological crystalline insulator. This is a quantum material that has been theoretically predicted for more than a decade but had remained inaccessible due to materials challenges.

Chronic pain affects more than 50 million Americans, yet for decades, treatment options for pain that persists in the absence of inflammation have been limited. Seventy-five percent of these patients, disproportionately women, experience pain that is inadequately managed by current therapeutics.

Even a short afternoon nap can help the brain recover and improve its ability to learn. In a study published on January 22, 2026, in the journal NeuroImage, researchers at the Medical Center–University of Freiburg (Germany), Geneva University Hospitals (HUG) and University of Geneva (UNIGE), show that even a nap is enough to reorganize connections between nerve cells so that new information can be stored more effectively.

Google is leveraging its artificial intelligence technology to open a new peephole for its dominant search engine to tailor answers that draw upon people's interests, habits, travel itineraries and photo libraries.

An international research team led by scientists at Waseda University and Tohoku University has discovered an extraordinary quasar in the early universe that hosts one of the fastest-growing supermassive black holes known at this mass scale. Observations with the Subaru Telescope reveal a striking, rule-breaking combination: the quasar is undergoing extremely rapid accretion while simultaneously shining brightly in X-rays and producing strong radio emission from a jet—features that many theoretical models do not expect to coexist. This unexpected juxtaposition of phenomena offers a new perspective on how supermassive black holes grow in the early universe.

With pedestrian fatalities—particularly in public transit areas—continuing to rise across the country, researchers at the University of Massachusetts Amherst have determined the top risk factors of pedestrian-vehicle crashes at bus stops to recommend potential solutions. While their comprehensive analysis of bus stops focused on Massachusetts, the researchers are excited about the generalizability of the findings and application to other locations.

At a recent party, another guest, a nurse, asked what I do for a living. I explained that as a health policy researcher, my work focuses on helping health-care systems coordinate care for dementia as effectively as for major conditions like cancer, diabetes or stroke. She stopped me mid-sentence.

Women who use water immersion during labor and birth experience better maternal and neonatal outcomes compared to those who receive epidural anesthesia, according to a study led by midwife Soledad Carreguí, in collaboration with researchers from the La Plana Health Department (Castelló) and the Departments of Computer Languages and Systems and Nursing at the Universitat Jaume I.

The vision of a fully connected world is rapidly becoming a reality through the Internet of Things (IoT)—a growing network of physical devices that collect and share data over the Internet, including everything from small sensors to autonomous vehicles and industrial equipment.

NASA researchers successfully completed a high-speed taxi test of a scale model of a design that could make future aircraft more efficient by improving how air flows across a wing's surface, saving fuel and money.

Researchers at the Icahn School of Medicine at Mount Sinai have characterized how cellular senescence—a biological process in which aging cells change how they function—is associated with human brain structure in both development and late life.

The International Society for Stem Cell Research (ISSCR) has released "Charting the Translational Pathway: ISSCR Best Practices for the Development of Pluripotent Stem Cell (PSC)-Derived Therapies," a new paper highlighting some of the most critical aspects of the ISSCR's breakthrough interactive resource designed to transform how PSC-derived therapies are developed, evaluated, and advanced toward clinical and commercial success.

The human gut is home to trillions of beneficial microbes that play a crucial role in health. Disruptions in this delicate community of bacteria and viruses—called the gut microbiome—have been linked to obesity, asthma and cancer, among other illnesses. Yet quick diagnostic tools to identify issues within the microbiome that could be addressed to treat these conditions are lacking.

A new study reveals that age-related changes in the gut microbiota directly impair intestinal stem cell (ISC) function and that restoring a youthful microbial environment can reverse this decline.

An international research team has succeeded in deciphering a key mechanism that controls the growth of pancreatic cancers. The scientists identified a potential central mechanism by which cancer cells protect themselves from attack by the body's own immune system. Blocking this mechanism resulted in a dramatic reduction in tumors in laboratory animals. Could this mark a shift in how we think about cancer therapy?

Researchers at Queen Mary's Barts Cancer Institute have found a more active approach to monitoring and treating people with a rare eye cancer (known as uveal melanoma) that has spread to the liver could help some patients to live longer.

Long-distance cyclists can preserve fat-free body mass while on a plant-based diet, according to new research involving a University of Alberta nutrition expert.

A research team affiliated with UNIST has unveiled a new technology that can convert seawater into clean drinking water using only sunlight, without any external power source. This breakthrough could play a crucial role in solving water shortages in developing countries and remote island communities where electricity is often unavailable.

Microalgae‑based architecture is gaining attention globally as a sustainable design solution, and the concept could soon become a reality in Western Australia.

Colorado State University has partnered with Microsoft to pilot a university-wide artificial intelligence system similar to ChatGPT that places the land-grant institution at the front of the pack in collaborations between higher education and AI companies.

As artificial intelligence threatens to upend job markets in countries around the world, Nvidia Corp. Chief Executive Officer Jensen Huang brushed off longer term concerns and made the case that skilled vocational workers are seeing increasing demand now.

A study led by UC Riverside researchers offers a practical fix to one of artificial intelligence's toughest challenges by enabling AI systems to reason more like humans—without requiring new training data beyond test questions.

Are generative artificial intelligence systems such as ChatGPT truly creative? A research team led by Professor Karim Jerbi from the Department of Psychology at the Université de Montréal, and including AI pioneer Yoshua Bengio, also a professor at Université de Montréal, has just published the largest comparative study ever conducted on the creativity of large language models versus humans.

Thermal management is essential for reducing future heating and cooling energy consumption. Notably, the near-infrared (NIR) component of sunlight is closely associated with heat absorption.

Demand for lithium is skyrocketing as factories across the world churn out electric vehicles and the massive batteries that make wind turbines and solar panels reliable sources of energy. Unfortunately, current methods for producing lithium are slow and require high-quality feedstocks that are found in relatively few locations on the planet. Ironically, the environmental costs are also significant: refining the mineral behind clean energy requires large amounts of land and pollutes water supplies that local communities depend on.

Researchers at the Department of Energy's Oak Ridge National Laboratory have developed a novel extrusion system that combines multiple 3D-printing extruders into a single, high-output stream via specially designed nozzles. This system matches the speed of larger extruders while providing greater flexibility, precision and multi-material printing capabilities.

The ubiquity of smart devices—not just phones and watches, but lights, refrigerators, doorbells and more, all constantly recording and transmitting data—is creating massive volumes of digital information that drain energy and slow data transmission speeds. With the rising use of artificial intelligence in industries ranging from health care and finance to transportation and manufacturing, addressing the issue is becoming more pressing.

People have become used to living with AI fairly quickly. ChatGPT is barely three years old, but has changed the way many of us communicate or deal with large amounts of information.

Most electronics are built on flat, stiff boards, which makes it incredibly difficult to fit them onto curved and irregular shapes we find in the real world, such as human limbs or curved aircraft wings. While flexible electronics have made some progress, they are often not durable enough or are too complex to manufacture for everyday use.

A new portable reactor based on a solid oxide fuel cell solves thermal management and safety issues, as reported by researchers from Japan. This miniaturized reactor can start up rapidly within five minutes at room temperature and demonstrate electric power generation. Featuring an innovative structural design with high thermal insulation and a multilayered insulation system, this microreactor design could be used to power a wide variety of edge devices.

YouTube announced plans on Wednesday to allow its users this year to create AI versions of themselves for video sharing, matching a feature from Sora, the video-creation app from ChatGPT-maker OpenAI.