Good news, everyone!

There's always a touch of melancholy when a chapter that has absorbed years of work comes to an end. In the case of the Atacama Cosmology Telescope (ACT), those years amount to nearly 20—and now the telescope has completed its mission. Yet some endings are also important beginnings, opening new paths for the entire scientific community.

When the center of protests against immigration enforcement switched recently to Charlotte, North Carolina, so did the frogs.

Two new reviews show strong and consistent evidence that HPV vaccines are effective in preventing cervical cancer and pre-cancerous changes, especially when given to young people before they are exposed to the virus. The papers are published in the Cochrane Database of Systematic Reviews.

Following the federal government's changes to COVID-19 vaccine eligibility and recommendations in 2025, many people are wondering whether they can get COVID-19 vaccines for themselves or their children.

In medieval England, peasants on some estates were entitled to a range of sick, annual and bereavement leave that could rival those of many workers in the UK today.

If the NHS recommended it, would people test their own hearing at home and use self-fitting hearing aids?

An emerging artificial intelligence-powered system developed at Penn Medicine has tripled the speed of fax processing and cut a full week off the new patient intake process—freeing up thousands of staff hours. The system, called coordn8, was created by the Penn Medicine Center for Health Care Transformation and Innovation (CHTI) and is detailed in a new paper published this week in NEJM Catalyst.

A pair of snowy owls spotted along a Lake Michigan beach has drawn curious crowds and sparked happy speculation about how long the Arctic birds of prey will call Chicago home.

A tiny wearable sensor designed for thoroughbred racehorses can identify horses at elevated risk of catastrophic injury, according to a new study led by researchers at Washington State University.

Autonomous self-driving cars and taxis are already on the roads of San Francisco and Beijing. There are also autonomous tram-style services around Oxfordshire and Dubai.

Artificial intelligence is fascinating, transformative and increasingly woven into how we learn, work and make decisions.

A joint research team has made important progress in the field of photoneutron cross section measurement. The team proposed a substitution measurement method that avoids the use of expensive and hard-to-prepare high-purity isotope targets, successfully measuring the 65Cu(γ,n)64Cu reaction cross section with high precision. This method only relies on natural copper (natCu) and previously measured copper-63 (63Cu) data, without modifying experimental facility parameters, making it simple, efficient, and low-cost.

A new oral GLP-1 medication can help adults with obesity and type 2 diabetes lose more weight and improve their blood sugar levels compared to a placebo, according to findings from the ATTAIN-2 trial led by a UTHealth Houston researcher.

Peanut allergy is one of the most common food allergies, affecting between 1% and 2% of people living in the West. And, for many years, their prevalence has been rising.

An increasingly strong case is being made to bring inequality into discussions about climate change. The logic behind this has been set out by leading international institutions such as the International Labor Organization, the UN Environmental Program and the Network for Greening the Financial System.

This year's COP30 comes after the international Agreement on Marine Biological Diversity of Areas beyond National Jurisdiction (BBNJ) finally acquired the required number of ratification votes by United Nations member states.

Imagine powering long-haul aircraft and heavy ships with fuels derived from just air, water and renewable electricity. This is moving from science fiction to the verge of reality, thanks to the falling price of renewables like wind and solar.

For over 200 years, native oysters (Ostrea edulis) have been absent in Dublin Bay. Once abundant along the Irish coast, they thrived in the sheltered estuaries and tidal flats that shaped the city's maritime life.

The government's vision for higher education in England, set out in a recent policy paper, includes some changes that will benefit students from poorer backgrounds.

Ever eaten while doom-scrolling and realized you barely tasted anything? Or found your favorite pasta strangely bland after a stressful meeting, yet somehow delicious on a relaxed Saturday evening?

For Las Vegas to keep its taps flowing, Rep. Susie Lee says this one drought measure must survive federal spending purges: water recycling.

The 2025 United Nations Climate Change Conference (sometimes referred to as COP30) is taking place in Brazil.

As the climate crisis accelerates, there's a desperate need to rapidly reduce carbon dioxide levels in the atmosphere, both by slashing emissions and by pulling carbon out of the air.

If I asked you to imagine your dream snog, chances are it wouldn't be with a Neanderthal; burly and hirsute as they may be. However, my team's new research suggests that these squat beefcakes might have been right up your ancestors' street.

Memory T cells are a special type of white blood cell that "remember" past infections and vaccines, helping our bodies to quickly respond if we encounter the same germs again. These cells are found throughout the body: some circulate in the blood, while others settle down as "residents" in tissues like the lungs, intestines and lymphoid organs (such as the spleen and lymph nodes).

Hydrogenases catalyze the reversible splitting and production of hydrogen gas (H2), using complex catalytic cofactors comprising Earth-abundant nickel and/or iron ions. These enzymes, especially the [NiFe]-hydrogenases (fig. 1), are remarkably efficient, making them inspiring models for clean-energy technologies. Yet despite extensive study by many groups worldwide, key steps in their catalytic cycle have remained difficult to observe.

Centuries before Monopoly, there was Patolli, a high-stakes Mesoamerican game of strategy and luck where players wagered crops and wealth as they raced their opponents around a cross-shaped board.

A key objective of electronics engineers is to further reduce the size of devices, while also boosting their speed, performance and efficiency. Two-dimensional (2D) semiconductors, single-layer and thin materials with a controllable electrical conductivity, have been found to be particularly promising for the development of smaller electronics.

Quantum ground states are the states at which quantum systems have the minimum possible energy. Quantum computers are increasingly being used to analyze the ground states of interesting systems, which could in turn inform the design of new materials, chemical compounds, pharmaceutical drugs and other valuable goods.

A new analysis published in the journal BioScience challenges conventional conservation approaches by demonstrating that traditional livestock grazing on rangelands represents a crucial but often overlooked strategy for protecting global biodiversity.

Researchers at Washington University School of Medicine in St. Louis, along with collaborators at Northwestern University, have developed a noninvasive approach to treat one of the most aggressive and deadly brain cancers. Their technology uses precisely engineered structures assembled from nano-size materials to deliver potent tumor-fighting medicine to the brain through nasal drops. The novel delivery method is less invasive than similar treatments in development and was shown in mice to effectively treat glioblastoma by boosting the brain's immune response.

In associate professor Mauro Tambasco's lab, researchers at all levels work together to develop innovative approaches to fighting cancer.

Alzheimer's disease (AD), a progressive neurodegenerative disorder, is one of the leading causes of dementia worldwide, and currently has no definitive cure. Although antibody-based therapies that target amyloid β (Aβ) have recently been developed, their clinical effectiveness remains limited. These treatments can be costly and cause immune-related side effects, highlighting the need for safer, affordable, and widely accessible approaches that can slow the progression of AD.

Crimean-Congo hemorrhagic fever (CCHF) is one of the world's most dangerous yet overlooked infectious diseases. Spread by ticks and livestock, the virus causes sudden fever, organ failure, and internal bleeding, killing up to 40% of those infected. Outbreaks have been reported across parts of Africa, Asia, Eastern Europe, and the Middle East. Despite decades of research, no approved vaccines or treatments exist.

University of Minnesota Medical School researchers have shown that reducing chronic inflammation can significantly protect against age-related macular degeneration (AMD)-like pathology in preclinical models. The findings were recently published in Cell Death & Disease.

In Black adults, computed tomography colonography (CTC) is cost-effective for colorectal cancer (CRC) screening, according to a study published online Nov. 12 in Cancer Medicine.

Type 1 diabetes (T1D) impacts nearly two million Americans, and by the time most people learn they have it, most of the body's insulin-producing cells are destroyed. Now, pinpointing a hidden group of immune "attack" cells in the pancreatic lymph nodes that appear earlier in the disease could offer the first real chance to detect—and even stop—T1D, according to new research from the Perelman School of Medicine at the University of Pennsylvania detailed in Science Immunology.

Pancreatic cancer is the deadliest form of cancer worldwide, mainly because the disease is often discovered late. Symptoms associated with these tumors are often non-specific, so patients and doctors do not immediately suspect cancer. Moreover, these tumors are difficult to detect in the early stages on abdominal CT scans. Once the diagnosis is made, curative treatment is usually no longer possible. Only 10% of patients survive beyond five years.

We owe a lot to tissue resident memory T cells (TRM). These specialized immune cells are among the body's first responders to disease.

Researchers at Karolinska Institutet in Sweden have identified a brain circuit that can drive repetitive and compulsive behaviors in mice, even when natural rewards such as food or social contact are available. The study has been published in the journal Science Advances and may contribute to increased knowledge about obsessive-compulsive disorder and addiction.

A joint research team from NIMS and Toyo Tanso has developed a carbon electrode that enables stable operation of a 1-Wh-class stacked lithium-air battery, achieving higher output, longer life and scalability simultaneously.

New York City's thousands of traffic cameras capture endless hours of footage each day, but analyzing that video to identify safety problems and implement improvements typically requires resources that most transportation agencies don't have.

Japanese local authorities approved the restart of the world's biggest nuclear plant on Friday for the first time since the 2011 Fukushima disaster.

Researchers have discovered that ferroelectric fluids can harness an overlooked transverse electrostatic force (TEF) to rise over 80 mm, without magnets or high voltages. By exploiting the fluid's spontaneous polarization and exceptionally high dielectric constant, they achieved a strong TEF, previously thought unattainable in conventional electrostatics.

A research team affiliated with UNIST has unveiled a novel thermoelectric (TE) film, capable of powering LED lights using a mere 1.5°C temperature difference between the human body and ambient air. This innovative technology promises new possibilities for self-powered wearable devices and energy-harvesting applications.

Solar panels made from silicon already adorn rooftops and vast fields around the world—but they are reaching their performance limits. Researchers are now pairing silicon with a promising material called perovskite to capture more sunlight and generate more electricity within the same area.

The ability to analyze the brain's neural connectivity is emerging as a key foundation for brain-computer interface (BCI) technologies, such as controlling artificial limbs and enhancing human intelligence. To make these analyses more precise, it is critical to quickly and accurately interpret the complex signals from many neurons in the brain.

A new Australian study has smashed the myth that generative AI systems such as ChatGPT could soon replace society's most creative playwrights, authors, songwriters, artists and scriptwriters.

OpenAI and Taiwan electronics giant Foxconn have agreed to a partnership to design and manufacture key equipment for artificial intelligence data centers in the U.S. as part of ambitious plans to fortify American AI infrastructure.

The shipbuilding industry is on the verge of a major leap forward. Timo Alho's doctoral dissertation at the University of Vaasa introduces a pioneering power management strategy that prevents ship blackouts. In Alho's management principle, the vessel's electrical equipment is capable of independently supporting the ship's grid without centralized commands. This makes the vessel's power systems significantly more fault-tolerant than before.

You've just put a dollar into a machine to play a song and it stopped playing after a few seconds. You put in another dollar and the tune stops after a minute. You can't get your dollars back and can't listen to the song you want. But what if you had known ahead of time what would happen, and could have saved yourself the money and frustration?

Soon, researchers may be able to create movies of their favorite protein or virus better and faster than ever before. Researchers at the Department of Energy's SLAC National Accelerator Laboratory have pioneered a new machine learning method—called X-RAI (X-Ray single particle imaging with Amortized Inference)—that can "look" at millions of X-ray laser-generated images and create a three-dimensional reconstruction of the target particle. The team recently reported their findings in Nature Communications.

By studying the theoretical limits of how light can be used to perform computation, Cornell researchers have uncovered new insights and strategies for designing energy-efficient optical computing systems.

Researchers at the Institute of Science Tokyo have developed a neural-network-based 3D imaging technique that can precisely measure moving objects—a task long considered extremely challenging for conventional optical systems.

Reducing the U.K.'s energy demand could help the country reach its net zero target faster and at half the cost compared to relying mainly on supply-side technologies, according to new research by energy experts.

The poplar (Populus alba) has a unique survival strategy: when exposed to hot and dry conditions, it curls its leaves to expose the ventral surface, reflecting sunlight, and at night, the moisture condensed on the leaf surface releases latent heat to prevent frost damage. Plants have evolved such intricate mechanisms in response to dynamic environmental fluctuations in diurnal and seasonal temperature cycles, light intensity, and humidity, but there have been few instances of realizing such a sophisticated thermal management system with artificial materials.

Paper packaging is a sustainable alternative to plastic. However, as it is permeable to air, food packaged in paper loses its flavor over time, and undesirable substances such as solvents can penetrate the packaging. Up to now, extensive tests were necessary for each type of paper to determine to what extent and how quickly this happens.